The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB<sub>1</sub> Cannabinoid Receptor.

Prüser, Jan Lukas; Ramer, Robert; Wittig, Felix; Ivanov, Igor; Merkord, Jutta; Hinz, Burkhard

The Monoacylglycerol Lipase Inhibitor JZL184 Inhibits Lung Cancer Cell Invasion and Metastasis via the CB₁ Cannabinoid Receptor.

Prüser, Jan Lukas; Ramer, Robert; Wittig, Felix; Ivanov, Igor; Merkord, Jutta; Hinz, Burkhard.

Afiliação

Prüser JL; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany.
Ramer R; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany.
Wittig F; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany.
Ivanov I; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany.
Merkord J; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany.
Hinz B; Institute of Pharmacology and Toxicology, Rostock University Medical Center, Rostock, Germany. burkhard.hinz@med.uni-rostock.de.

Mol Cancer Ther ; 20(5): 787-802, 2021 05.

Article em En | MEDLINE | ID: mdl-33632876

Assuntos

Ansiolíticos/uso terapêutico; Benzodioxóis/uso terapêutico; Neoplasias Pulmonares/tratamento farmacológico; Neoplasias Pulmonares/genética; Piperidinas/uso terapêutico; Receptores de Canabinoides/genética; Animais; Ansiolíticos/farmacologia; Benzodioxóis/farmacologia; Modelos Animais de Doenças; Humanos; Camundongos; Camundongos Nus; Invasividade Neoplásica; Metástase Neoplásica; Piperidinas/farmacologia; Transfecção

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperidinas / Ansiolíticos / Receptores de Canabinoides / Benzodioxóis / Neoplasias Pulmonares Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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