[Screening of potential non-azole inhibitors of lanosterol14-alpha demethylase (CYP51) of Candida fungi].

Kaluzhskiy, L A; Ershov, P V; Yablokov, E O; Mezentsev, Y V; Gnedenko, O V; Shkel, T V; Gilep, A A; Usanov, S A; Ivanov, A S

[Screening of potential non-azole inhibitors of lanosterol14-alpha demethylase (CYP51) of Candida fungi]. / Skrining potentsial'nykh neazol'nykh ingibitorov 14-al'fademetilazy (CYP51) gribov roda Candida.

Kaluzhskiy, L A; Ershov, P V; Yablokov, E O; Mezentsev, Y V; Gnedenko, O V; Shkel, T V; Gilep, A A; Usanov, S A; Ivanov, A S.

Afiliação

Kaluzhskiy LA; Institute of Biomedical Chemistry, Moscow, Russia.
Ershov PV; Institute of Biomedical Chemistry, Moscow, Russia.
Yablokov EO; Institute of Biomedical Chemistry, Moscow, Russia.
Mezentsev YV; Institute of Biomedical Chemistry, Moscow, Russia.
Gnedenko OV; Institute of Biomedical Chemistry, Moscow, Russia.
Shkel TV; Institute of Bioorganic Chemistry, Minsk, Belarus.
Gilep AA; Institute of Bioorganic Chemistry, Minsk, Belarus.
Usanov SA; Institute of Bioorganic Chemistry, Minsk, Belarus.
Ivanov AS; Institute of Biomedical Chemistry, Moscow, Russia.

Biomed Khim ; 67(1): 42-50, 2021 Jan.

Article em Ru | MEDLINE | ID: mdl-33645521

Assuntos

Antifúngicos; Candida; Inibidores de 14-alfa Desmetilase/farmacologia; Antifúngicos/farmacologia; Candida albicans; Sistema Enzimático do Citocromo P-450; Esterol 14-Desmetilase

Palavras-chave

CYP51 inhibitors; antimycotic; docking; drugs; surface plasmon resonance

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Candida / Antifúngicos Tipo de estudo: Diagnostic_studies / Prognostic_studies / Screening_studies Idioma: Ru Ano de publicação: 2021 Tipo de documento: Article

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