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The Immune Response and Effectiveness of COVID-19 Therapies.
Tavasolian, Fataneh; Hatam, Gholam Reza; Mosawi, Sayed Hussain; Saadi, Mahdiyar Iravani; Abdollahi, Elham; Jamialahmadi, Tannaz; Sathyapalan, Thozhukat; Sahebkar, Amirhossein.
Afiliação
  • Tavasolian F; Department of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
  • Hatam GR; Basic Sciences in Infectious Diseases Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Mosawi SH; Medical Sciences Research Center, Ghalib University, Kabul, Afghanistan.
  • Saadi MI; Hematology Research Center, Department of Hematology, Medical Oncology and Stem Cell Transplantation, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Abdollahi E; Department of Medical Immunology and Allergy, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Jamialahmadi T; Biotechnology Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.
  • Sathyapalan T; Department of Food Science and Technology, Quchan Branch, Islamic Azad University, Quchan, Iran.
  • Sahebkar A; Department of Nutrition, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Adv Exp Med Biol ; 1321: 115-126, 2021.
Article em En | MEDLINE | ID: mdl-33656718
ABSTRACT
Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is highly pathogenic with relatively high mortality and morbidity. In addition to pneumonia, acute respiratory distress syndrome, and microembolic disorder, a high proportion of patients with SARS-CoV-2 develop lymphopenia and cytokine storm disorder. This review explores the underlying mechanisms behind the pathogenesis of SARS-CoV-2, especially the immune mechanisms, which could be potentially used as therapeutic targets for the management of COVID-19.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Desconforto Respiratório / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Síndrome do Desconforto Respiratório / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article