Cas9 deactivation with photocleavable guide RNAs.

Zou, Roger S; Liu, Yang; Wu, Bin; Ha, Taekjip

Zou, Roger S; Liu, Yang; Wu, Bin; Ha, Taekjip.

Afiliação

Zou RS; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA.
Liu Y; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD 21205, USA.
Wu B; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD 21205, USA.
Ha T; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Biophysics and Biophysical Chemistry, Johns Hopkins University, Baltimore, MD 21205, USA; Department of Biophysics, Johns Hopkins University, Baltimore, MD 21205, USA; Howard Hughes Medical Instit

Mol Cell ; 81(7): 1553-1565.e8, 2021 04 01.

Article em En | MEDLINE | ID: mdl-33662274

Assuntos

Proteína 9 Associada à CRISPR/química; Sistemas CRISPR-Cas; Dano ao DNA; Edição de Genes; RNA Guia de Cinetoplastídeos/química; Proteína 9 Associada à CRISPR/metabolismo; RNA Guia de Cinetoplastídeos/metabolismo

Palavras-chave

CRISPR; Cas9; DNA repair; deactivation; genome editing; specificity

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Dano ao DNA / RNA Guia de Cinetoplastídeos / Sistemas CRISPR-Cas / Edição de Genes / Proteína 9 Associada à CRISPR Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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