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Therapeutic Interleukin-6 Trans-signaling Inhibition by Olamkicept (sgp130Fc) in Patients With Active Inflammatory Bowel Disease.
Schreiber, Stefan; Aden, Konrad; Bernardes, Joana P; Conrad, Claudio; Tran, Florian; Höper, Hanna; Volk, Valery; Mishra, Neha; Blase, Johanna Ira; Nikolaus, Susanna; Bethge, Johannes; Kühbacher, Tanja; Röcken, Christoph; Chen, Minhu; Cottingham, Ian; Petri, Niclas; Rasmussen, Birgitte B; Lokau, Juliane; Lenk, Lennart; Garbers, Christoph; Feuerhake, Friedrich; Rose-John, Stefan; Waetzig, Georg H; Rosenstiel, Philip.
Afiliação
  • Schreiber S; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: s.schreiber@mucosa.de.
  • Aden K; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Bernardes JP; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Conrad C; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Tran F; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Höper H; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Volk V; Institute for Pathology, Medizinische Hochschule Hannover, Hannover, Germany.
  • Mishra N; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Blase JI; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Nikolaus S; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Bethge J; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Kühbacher T; Asklepios Westklinikum Hamburg, Hamburg, Germany.
  • Röcken C; Department of Pathology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Chen M; The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
  • Cottingham I; Ferring Pharmaceuticals A/S, Copenhagen S, Denmark.
  • Petri N; Ferring Pharmaceuticals A/S, Copenhagen S, Denmark.
  • Rasmussen BB; Ferring Pharmaceuticals A/S, Copenhagen S, Denmark.
  • Lokau J; Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany.
  • Lenk L; Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany.
  • Garbers C; Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany.
  • Feuerhake F; Institute for Pathology, Medizinische Hochschule Hannover, Hannover, Germany.
  • Rose-John S; Institute of Biochemistry, Kiel University, Kiel, Germany.
  • Waetzig GH; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Conaris Research Institute AG, Kiel, Germany.
  • Rosenstiel P; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: p.rosenstiel@mucosa.de.
Gastroenterology ; 160(7): 2354-2366.e11, 2021 06.
Article em En | MEDLINE | ID: mdl-33667488
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Transdução de Sinais / Colite Ulcerativa / Doença de Crohn / Interleucina-6 Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Recombinantes de Fusão / Transdução de Sinais / Colite Ulcerativa / Doença de Crohn / Interleucina-6 Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article