Phenomes: the current frontier in animal breeding.
Genet Sel Evol
; 53(1): 22, 2021 Mar 05.
Article
em En
| MEDLINE
| ID: mdl-33673800
ABSTRACT
Improvements in genomic technologies have outpaced the most optimistic predictions, allowing industry-scale application of genomic selection. However, only marginal gains in genetic prediction accuracy can now be expected by increasing marker density up to sequence, unless causative mutations are identified. We argue that some of the most scientifically disrupting and industry-relevant challenges relate to 'phenomics' instead of 'genomics'. Thanks to developments in sensor technology and artificial intelligence, there is a wide range of analytical tools that are already available and many more will be developed. We can now address some of the pressing societal demands on the industry, such as animal welfare concerns or efficiency in the use of resources. From the statistical and computational point of view, phenomics raises two important issues that require further work penalization and dimension reduction. This will be complicated by the inherent heterogeneity and 'missingness' of the data. Overall, we can expect that precision livestock technologies will make it possible to collect hundreds of traits on a continuous basis from large numbers of animals. Perhaps the main revolution will come from redesigning animal breeding schemes to explicitly allow for high-dimensional phenomics. In the meantime, phenomics data will definitely enlighten our knowledge on the biological basis of phenotypes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Gado
/
Seleção Artificial
/
Fenômica
Limite:
Animals
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article