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NMR and EPR reveal a compaction of the RNA-binding protein FUS upon droplet formation.
Emmanouilidis, Leonidas; Esteban-Hofer, Laura; Damberger, Fred F; de Vries, Tebbe; Nguyen, Cristina K X; Ibáñez, Luis Fábregas; Mergenthal, Simon; Klotzsch, Enrico; Yulikov, Maxim; Jeschke, Gunnar; Allain, Frédéric H-T.
Afiliação
  • Emmanouilidis L; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland. leonidas@bc.biol.ethz.ch.
  • Esteban-Hofer L; Department of Chemistry and Applied Biosciences, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
  • Damberger FF; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
  • de Vries T; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
  • Nguyen CKX; Department of Biology, Institute of Biochemistry, ETH Zurich, Zurich, Switzerland.
  • Ibáñez LF; Department of Chemistry and Applied Biosciences, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
  • Mergenthal S; Institute for Biology, Experimental Biophysics/Mechanobiology, Humboldt University of Berlin, Berlin, Germany.
  • Klotzsch E; Institute for Biology, Experimental Biophysics/Mechanobiology, Humboldt University of Berlin, Berlin, Germany.
  • Yulikov M; Laboratory of Applied Mechanobiology, Department for Health Sciences and Technology, ETH Zurich, Zurich, Switzerland.
  • Jeschke G; Department of Chemistry and Applied Biosciences, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland.
  • Allain FH; Department of Chemistry and Applied Biosciences, Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland. gjeschke@ethz.ch.
Nat Chem Biol ; 17(5): 608-614, 2021 05.
Article em En | MEDLINE | ID: mdl-33686294
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sefarose / Hidrogéis / Crioprotetores / Proteína FUS de Ligação a RNA Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sefarose / Hidrogéis / Crioprotetores / Proteína FUS de Ligação a RNA Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article