Tissue-specific enhancer functional networks for associating distal regulatory regions to disease.

Chen, Xi; Zhou, Jian; Zhang, Ran; Wong, Aaron K; Park, Christopher Y; Theesfeld, Chandra L; Troyanskaya, Olga G

Chen, Xi; Zhou, Jian; Zhang, Ran; Wong, Aaron K; Park, Christopher Y; Theesfeld, Chandra L; Troyanskaya, Olga G.

Afiliação

Chen X; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA.
Zhou J; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Zhang R; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Wong AK; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA.
Park CY; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA.
Theesfeld CL; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA.
Troyanskaya OG; Center for Computational Biology, Flatiron Institute, Simons Foundation, New York, NY 10010, USA; Lewis-Sigler Institute for Integrative Genomics, Princeton University, Princeton, NJ 08544, USA; Department of Computer Science, Princeton University, Princeton, NJ 08544, USA. Electronic address: ogt@c

Cell Syst ; 12(4): 353-362.e6, 2021 04 21.

Article em En | MEDLINE | ID: mdl-33689683

Assuntos

Elementos Facilitadores Genéticos/genética; Redes Reguladoras de Genes/genética; Humanos

Palavras-chave

GWAS; autism; brain; de novo mutation; enhancer; functional network

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Elementos Facilitadores Genéticos / Redes Reguladoras de Genes Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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