The Enigma of 2-Cys Peroxiredoxins: What Are Their Roles?
Biochemistry (Mosc)
; 86(1): 84-91, 2021 Jan.
Article
em En
| MEDLINE
| ID: mdl-33705284
ABSTRACT
2-Cys peroxiredoxins are abundant thiol proteins that react efficiently with a wide range of peroxides. Unlike other enzymes, their exceptionally high reactivity does not rely on cofactors. The mechanism of oxidation and reduction of peroxiredoxins places them in a good position to act as antioxidants as well as key players in redox signaling. Understanding of the intimate details of peroxiredoxin functioning is important for translational research.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Peroxirredoxinas
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article