Effect of embedded metal fragments on urinary metal levels and kidney biomarkers in the Sprague-Dawley rat.

Hoffman, Jessica F; Vergara, Vernieda B; Fan, Anya X; Kalinich, John F.

Afiliação

Hoffman JF; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, MD, USA.
Vergara VB; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, MD, USA.
Fan AX; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, MD, USA.
Kalinich JF; Internal Contamination and Metal Toxicity Program, Armed Forces Radiobiology Research Institute, Uniformed Services University, Bethesda, MD, USA.

Toxicol Rep ; 8: 463-480, 2021.

Article em En | MEDLINE | ID: mdl-33717999

Palavras-chave

AAALAC-I, Association for Assessment and Accreditation of Laboratory Animal Care International; AFRRI, Armed Forces Radiobiology Research Institute; ALB, Albumin; ALP, Alkaline phosphatase; Al, Aluminum; B2m, Beta-2-microglobulin; Biomarker; Co, Cobalt; Cu, Copper; DU, Depleted uranium; DoD, Department of Defense; Embedded metals; Fe, Iron; IACUC, Institutional Animal Care and Use Committee; ICP-MS, Inductively coupled plasma-mass spectroscopy; IL-18, Interleukin-18; KIM-1, Kidney injury molecule-1; Kidney; LoD, Limit of detection; LoQ, Limit of quantitation; NAG, N-acetyl-beta-d-glucosaminidase; NGAL, Neutrophil gelatinase-associated lipocalin; Ni, Nickel; OPN, Osteopontin; Pb, Lead; RBP, Retinal binding protein; Rat; Ta, Tantalum; Urine; W, Tungsten

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article