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Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart.
Walejko, Jacquelyn M; Christopher, Bridgette A; Crown, Scott B; Zhang, Guo-Fang; Pickar-Oliver, Adrian; Yoneshiro, Takeshi; Foster, Matthew W; Page, Stephani; van Vliet, Stephan; Ilkayeva, Olga; Muehlbauer, Michael J; Carson, Matthew W; Brozinick, Joseph T; Hammond, Craig D; Gimeno, Ruth E; Moseley, M Arthur; Kajimura, Shingo; Gersbach, Charles A; Newgard, Christopher B; White, Phillip J; McGarrah, Robert W.
Afiliação
  • Walejko JM; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Christopher BA; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Crown SB; Department of Medicine, Division of Cardiology, Duke University School of Medicine, Durham, NC, USA.
  • Zhang GF; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Pickar-Oliver A; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Yoneshiro T; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.
  • Foster MW; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
  • Page S; Department of Biomedical Engineering, Duke University, Durham, NC, USA.
  • van Vliet S; Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
  • Ilkayeva O; UCSF Diabetes Center, San Francisco, CA, USA.
  • Muehlbauer MJ; Duke Proteomics and Metabolomics Shared Resource, Duke University School of Medicine, Durham, NC, USA.
  • Carson MW; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Brozinick JT; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Hammond CD; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Gimeno RE; Department of Medicine, Division of Endocrinology, Metabolism and Nutrition, Duke University School of Medicine, Durham, NC, USA.
  • Moseley MA; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
  • Kajimura S; Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, USA.
  • Gersbach CA; Sarah W. Stedman Nutrition and Metabolism Center, Duke University School of Medicine, Durham, NC, USA.
  • Newgard CB; Eli Lilly and Company, Indianapolis, IN, US.
  • White PJ; Eli Lilly and Company, Indianapolis, IN, US.
  • McGarrah RW; Eli Lilly and Company, Indianapolis, IN, US.
Nat Commun ; 12(1): 1680, 2021 03 15.
Article em En | MEDLINE | ID: mdl-33723250
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemiterpenos / Aminoácidos de Cadeia Ramificada / Coração / Cetoácidos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Hemiterpenos / Aminoácidos de Cadeia Ramificada / Coração / Cetoácidos Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article