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Impaired Peyer's patch development in BOB.1/OBF.1-deficient mice.
Betzler, Annika C; Fiedler, Katja; Kokai, Enikö; Wirth, Thomas; Hoffmann, Thomas K; Brunner, Cornelia.
Afiliação
  • Betzler AC; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany.
  • Fiedler K; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany.
  • Kokai E; Institute of Physiological Chemistry, Ulm University, Ulm, Germany.
  • Wirth T; Institute of Physiological Chemistry, Ulm University, Ulm, Germany.
  • Hoffmann TK; Institute of Physiological Chemistry, Ulm University, Ulm, Germany.
  • Brunner C; Department of Oto-Rhino-Laryngology, Head and Neck Surgery, Ulm University Medical Center, Ulm, Germany.
Eur J Immunol ; 51(7): 1860-1863, 2021 07.
Article em En | MEDLINE | ID: mdl-33733501
ABSTRACT
BOB.1/OBF.1 expression regulates the transcription of direct and indirect target genes. We propose that BOB.1/OBF.1 affects CXCL13-CXCR5 signaling of LTinducer and LTorganizer cells during embryonic Peyer's patch organogenesis as well as of B cells and follicular dendritic cells during lymphocyte homing at postnatal stages of secondary lymphoid organ development.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nódulos Linfáticos Agregados / Transativadores Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Nódulos Linfáticos Agregados / Transativadores Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article