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Expression of PRIP, a phosphatidylinositol 4,5-bisphosphate binding protein, attenuates PI3K/AKT signaling and suppresses tumor growth in a xenograft mouse model.
Maetani, Yuka; Asano, Satoshi; Mizokami, Akiko; Yamawaki, Yosuke; Sano, Tomomi; Hirata, Masato; Irifune, Masahiro; Kanematsu, Takashi.
Afiliação
  • Maetani Y; Department of Cellular and Molecular Pharmacology, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan; Department of Dental Anesthesiology, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Asano S; Department of Cellular and Molecular Pharmacology, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Mizokami A; OBT Research Center, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan; Department of Cell Biology and Pharmacology, Faculty of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Yamawaki Y; Department of Cellular and Molecular Pharmacology, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan; Laboratory of Advanced Pharmacology, Daiichi University of Pharmacy, 22-1 Tamagawa-cho, Minami-ku, Fukuoka, 815-8511, Japan.
  • Sano T; Department of Cell Biology and Pharmacology, Faculty of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
  • Hirata M; Oral Medicine Research Center, Fukuoka Dental College, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0193, Japan.
  • Irifune M; Department of Dental Anesthesiology, Institute of Biomedical and Health Sciences, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan.
  • Kanematsu T; Department of Cellular and Molecular Pharmacology, Hiroshima University, 1-2-3, Kasumi, Minami-ku, Hiroshima, 734-8553, Japan; Department of Cell Biology and Pharmacology, Faculty of Dental Science, Kyushu University, 3-1-1, Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. Electronic address: taka-ka
Biochem Biophys Res Commun ; 552: 106-113, 2021 05 07.
Article em En | MEDLINE | ID: mdl-33743346
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Fosfatidilinositol 4,5-Difosfato / Fosfatidilinositol 3-Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Proto-Oncogênicas c-akt / Neoplasias Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas de Transporte / Fosfatidilinositol 4,5-Difosfato / Fosfatidilinositol 3-Quinases / Peptídeos e Proteínas de Sinalização Intracelular / Proteínas Proto-Oncogênicas c-akt / Neoplasias Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article