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Bioinspired artificial exosomes based on lipid nanoparticles carrying let-7b-5p promote angiogenesis in vitro and in vivo.
Aday, Sezin; Hazan-Halevy, Inbal; Chamorro-Jorganes, Aranzazu; Anwar, Maryam; Goldsmith, Meir; Beazley-Long, Nicholas; Sahoo, Susmita; Dogra, Navneet; Sweaad, Walid; Catapano, Francesco; Ozaki-Tan, Sho; Angelini, Gianni D; Madeddu, Paolo; Benest, Andrew V; Peer, Dan; Emanueli, Costanza.
Afiliação
  • Aday S; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK; Department of Bioengineering, University of Pennsylvania, Philadelphia, PA 19104, USA.
  • Hazan-Halevy I; Laboratory of Precision NanoMedicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
  • Chamorro-Jorganes A; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Anwar M; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Goldsmith M; Laboratory of Precision NanoMedicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
  • Beazley-Long N; Biodiscovery Institute, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK.
  • Sahoo S; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Dogra N; Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
  • Sweaad W; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Catapano F; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Ozaki-Tan S; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Angelini GD; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK.
  • Madeddu P; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK.
  • Benest AV; Biodiscovery Institute, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG7 2RD, UK.
  • Peer D; Laboratory of Precision NanoMedicine, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel. Electronic address: peer@tauex.tau.ac.il.
  • Emanueli C; Bristol Heart Institute, University of Bristol, Bristol BS2 8ED, UK; National Heart and Lung Institute, Imperial College London, London W12 0NN, UK. Electronic address: c.emanueli@imperial.ac.uk.
Mol Ther ; 29(7): 2239-2252, 2021 07 07.
Article em En | MEDLINE | ID: mdl-33744469

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização Fisiológica / MicroRNAs / Nanopartículas / Exossomos / Líquido Pericárdico / Vesículas Extracelulares / Lipossomos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização Fisiológica / MicroRNAs / Nanopartículas / Exossomos / Líquido Pericárdico / Vesículas Extracelulares / Lipossomos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article