Dipeptidyl peptidase-4 inhibitor, anagliptin, alters hepatic insulin clearance in relation to the glycemic status in Japanese individuals with type 2 diabetes.

Abe, Takahiro; Matsubayashi, Yasuhiro; Muragishi, Sayaka; Yoshida, Akihiro; Suganami, Hideki; Furusawa, Kenichi; Fujihara, Kazuya; Tanaka, Shiro; Kaku, Kohei; Sone, Hirohito

Dipeptidyl peptidase-4 inhibitor, anagliptin, alters hepatic insulin clearance in relation to the glycemic status in Japanese individuals with type 2 diabetes.

Abe, Takahiro; Matsubayashi, Yasuhiro; Muragishi, Sayaka; Yoshida, Akihiro; Suganami, Hideki; Furusawa, Kenichi; Fujihara, Kazuya; Tanaka, Shiro; Kaku, Kohei; Sone, Hirohito.

Afiliação

Abe T; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Matsubayashi Y; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Muragishi S; Kowa Co., Ltd., Tokyo, Japan.
Yoshida A; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Suganami H; Kowa Co., Ltd., Tokyo, Japan.
Furusawa K; Kowa Co., Ltd., Tokyo, Japan.
Fujihara K; Sanwa Kagaku Kenkyusho Co., Ltd., Nagoya, Japan.
Tanaka S; Department of Hematology, Endocrinology and Metabolism, Niigata University Faculty of Medicine, Niigata, Japan.
Kaku K; Department of Clinical Biostatistics, Graduate School of Medicine Kyoto University, Kyoto, Japan.
Sone H; Kawasaki Medical School, Okayama, Japan.

J Diabetes Investig ; 12(10): 1805-1815, 2021 Oct.

Article em En | MEDLINE | ID: mdl-33751849

Assuntos

Diabetes Mellitus Tipo 2/tratamento farmacológico; Inibidores da Dipeptidil Peptidase IV/uso terapêutico; Insulina/metabolismo; Fígado/metabolismo; Pirimidinas/uso terapêutico; Idoso; Povo Asiático; Diabetes Mellitus Tipo 2/metabolismo; Inibidores da Dipeptidil Peptidase IV/farmacologia; Método Duplo-Cego; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Pirimidinas/farmacologia

Palavras-chave

Dipeptidyl peptidase-4 inhibitor; Hepatic insulin clearance; Meal tolerance test

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirimidinas / Diabetes Mellitus Tipo 2 / Inibidores da Dipeptidil Peptidase IV / Insulina / Fígado Tipo de estudo: Clinical_trials / Prognostic_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google