Vitamin D/VDR signaling inhibits colitis by suppressing HIF-1&#945; activation in colonic epithelial cells.

Xue, Gang; Gao, Ruifang; Liu, Zhuanzhuan; Xu, Na; Cao, Yong; Zhao, Bin; Du, Jie

Vitamin D/VDR signaling inhibits colitis by suppressing HIF-1α activation in colonic epithelial cells.

Xue, Gang; Gao, Ruifang; Liu, Zhuanzhuan; Xu, Na; Cao, Yong; Zhao, Bin; Du, Jie.

Afiliação

Xue G; Department of Gastroenterology, Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China.
Gao R; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Liu Z; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Xu N; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Cao Y; Department of Gastroenterology, Division of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang, Liaoning, China.
Zhao B; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.
Du J; Shanxi Province Key Laboratory of Oral Diseases Prevention and New Materials, Shanxi Medical University School and Hospital of Stomatology, Taiyuan, Shanxi, China.

Am J Physiol Gastrointest Liver Physiol ; 320(5): G837-G846, 2021 05 01.

Article em En | MEDLINE | ID: mdl-33759562

Assuntos

Colite/metabolismo; Colo/metabolismo; Células Epiteliais/metabolismo; Subunidade alfa do Fator 1 Induzível por Hipóxia/metabolismo; Receptores de Calcitriol/metabolismo; Transdução de Sinais/fisiologia; Vitamina D/metabolismo; Animais; Linhagem Celular; Colo/efeitos dos fármacos; Células Epiteliais/efeitos dos fármacos; Humanos; Mucosa Intestinal/efeitos dos fármacos; Mucosa Intestinal/metabolismo; Camundongos; NF-kappa B/metabolismo; Transdução de Sinais/efeitos dos fármacos; Fator de Necrose Tumoral alfa/farmacologia

Palavras-chave

colonic epithelial cells; hypoxia-inducible factor 1; inflammatory bowel disease; vitamin D

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vitamina D / Transdução de Sinais / Receptores de Calcitriol / Colite / Colo / Células Epiteliais / Subunidade alfa do Fator 1 Induzível por Hipóxia Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google