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How to Develop and Prove High-Efficiency Selection of Ligands from Oligonucleotide Libraries: A Universal Framework for Aptamers and DNA-Encoded Small-Molecule Ligands.
Le, An T H; Krylova, Svetlana M; Beloborodov, Stanislav S; Wang, Tong Y; Hili, Ryan; Johnson, Philip E; Li, Feng; Veedu, Rakesh N; Belyanskaya, Svetlana; Krylov, Sergey N.
Afiliação
  • Le ATH; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
  • Krylova SM; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
  • Beloborodov SS; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
  • Wang TY; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
  • Hili R; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
  • Johnson PE; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
  • Li F; Department of Chemistry and Centre for Biotechnology, Brock University, 1812 Sir Isaac Brock Way, St. Catharines, Ontario L2S 3A1, Canada.
  • Veedu RN; Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University and Perron Institute for Neurological and Translational Science, Perth 6150, Australia.
  • Belyanskaya S; Anagenex, 10 Roessler Rd., Unit N, Woburn, Massachusetts 01801, United States.
  • Krylov SN; Department of Chemistry and Centre for Research on Biomolecular Interactions, York University, Toronto, Ontario M3J 1P3, Canada.
Anal Chem ; 93(13): 5343-5354, 2021 04 06.
Article em En | MEDLINE | ID: mdl-33764056

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Aptâmeros de Nucleotídeos Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: DNA / Aptâmeros de Nucleotídeos Tipo de estudo: Guideline / Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article