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Perilipin 2 downregulation in ß cells impairs insulin secretion under nutritional stress and damages mitochondria.
Mishra, Akansha; Liu, Siming; Promes, Joseph; Harata, Mikako; Sivitz, William; Fink, Brian; Bhardwaj, Gourav; O'Neill, Brian T; Kang, Chen; Sah, Rajan; Strack, Stefan; Stephens, Samuel; King, Timothy; Jackson, Laura; Greenberg, Andrew S; Anokye-Danso, Frederick; Ahima, Rexford S; Ankrum, James; Imai, Yumi.
Afiliação
  • Mishra A; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Liu S; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Promes J; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Harata M; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Sivitz W; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Fink B; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Bhardwaj G; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • O'Neill BT; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Kang C; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Sah R; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Strack S; Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, USA.
  • Stephens S; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • King T; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Jackson L; Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, USA.
  • Greenberg AS; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Anokye-Danso F; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Ahima RS; Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.
  • Ankrum J; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, Iowa, USA.
  • Imai Y; Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, USA.
JCI Insight ; 6(9)2021 05 10.
Article em En | MEDLINE | ID: mdl-33784258

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Células Secretoras de Insulina / Gotículas Lipídicas / Perilipina-2 / Secreção de Insulina Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Estresse Fisiológico / Células Secretoras de Insulina / Gotículas Lipídicas / Perilipina-2 / Secreção de Insulina Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article