Mood Disorder in Systemic Lupus Erythematosus Induced by Antiribosomal P Protein Antibodies Associated with Decreased Serum and Brain Tryptophan.

Cho, Takamasa; Sato, Hiroe; Wakamatsu, Ayako; Ohashi, Riuko; Ajioka, Yoichi; Uchiumi, Toshio; Goto, Shin; Narita, Ichiei; Kaneko, Yoshikatsu

Cho, Takamasa; Sato, Hiroe; Wakamatsu, Ayako; Ohashi, Riuko; Ajioka, Yoichi; Uchiumi, Toshio; Goto, Shin; Narita, Ichiei; Kaneko, Yoshikatsu.

Afiliação

Cho T; Division of Clinical Nephrology and Rheumatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9518510, Japan.
Sato H; Health Administration Center, Niigata University, Niigata 9502181, Japan.
Wakamatsu A; Division of Clinical Nephrology and Rheumatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9518510, Japan.
Ohashi R; Histopathology Core Facility, Faculty of Medicine, Niigata University, Niigata 9518510, Japan.
Ajioka Y; Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9518510, Japan; and.
Uchiumi T; Histopathology Core Facility, Faculty of Medicine, Niigata University, Niigata 9518510, Japan.
Goto S; Division of Molecular and Diagnostic Pathology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9518510, Japan; and.
Narita I; Department of Biology, Faculty of Science, Niigata University, Niigata 9502181, Japan.
Kaneko Y; Division of Clinical Nephrology and Rheumatology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata 9518510, Japan.

J Immunol ; 206(8): 1729-1739, 2021 04 15.

Article em En | MEDLINE | ID: mdl-33789980

Assuntos

Complexo Antígeno-Anticorpo/metabolismo; Encéfalo/metabolismo; Lúpus Eritematoso Sistêmico/metabolismo; Macrófagos/imunologia; Transtornos do Humor/prevenção & controle; Soro/metabolismo; Triptofano/metabolismo; Animais; Anticorpos Monoclonais/metabolismo; Autoanticorpos/metabolismo; Suplementos Nutricionais; Humanos; Hibridomas; Lúpus Eritematoso Sistêmico/complicações; Camundongos; Camundongos Endogâmicos BALB C; Camundongos Endogâmicos C57BL; Transtornos do Humor/etiologia; Fosfoproteínas/imunologia; Receptores de IgG/metabolismo; Proteínas Ribossômicas/imunologia; Triptofano/administração & dosagem; Fator de Necrose Tumoral alfa/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Triptofano / Encéfalo / Transtornos do Humor / Soro / Lúpus Eritematoso Sistêmico / Macrófagos / Complexo Antígeno-Anticorpo Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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