End-to-end continuous bioprocessing: Impact on facility design, cost of goods, and cost of development for monoclonal antibodies.

Mahal, Hanna; Branton, Harvey; Farid, Suzanne S

Mahal, Hanna; Branton, Harvey; Farid, Suzanne S.

Afiliação

Mahal H; The Advanced Centre for Biochemical Engineering, Department of Biochemical Engineering, University College London, London, UK.
Branton H; Centre for Process Innovation, Darlington, UK.
Farid SS; The Advanced Centre for Biochemical Engineering, Department of Biochemical Engineering, University College London, London, UK.

Biotechnol Bioeng ; 118(9): 3468-3485, 2021 09.

Article em En | MEDLINE | ID: mdl-33792918

Assuntos

Anticorpos Monoclonais; Técnicas de Cultura Celular por Lotes; Reatores Biológicos; Modelos Teóricos; Anticorpos Monoclonais/biossíntese; Anticorpos Monoclonais/química; Anticorpos Monoclonais/isolamento & purificação; Biotecnologia

Palavras-chave

chemistry, manufacturing and controls; cost of development; cost of goods; end-to-end continuous processing; monoclonal antibody manufacture; process economics

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Reatores Biológicos / Técnicas de Cultura Celular por Lotes / Modelos Teóricos / Anticorpos Monoclonais Tipo de estudo: Health_economic_evaluation / Prognostic_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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