First evidence of blaNDM-1 and blaOXA-23 carbapenemase genes in human body lice infesting a second-hand T-shirt in a street market in Italy.
Ann Ist Super Sanita
; 57(1): 33-36, 2021.
Article
em En
| MEDLINE
| ID: mdl-33797402
ABSTRACT
BACKGROUND:
The spread of carbapenems resistance is a public health concern. The main group of carbapenemases encoding the ß-lactamases activity (bla genes) is the Metallo-ß-lactamases (MBLs).METHODS:
The presence of carbapenemase blaOXA-23-like, blaOXA-40-like, blaOXA-51-like, blaOXA-58-like, and blaNDM-1 genes was screened by real time PCR in 26 Pediculus humanus insects identified from second-hand clothes in a local market in Central Italy. Bacteria diversity was also characterized through shotgun metagenomic amplification for a deep sequencing of the host-associated bacterial microbiomes.RESULTS:
The blaOXA-23 and blaNDM-1 carbapenemases genes were found and metagenomic analysis showed a great presence of Acinetobacter species.CONCLUSIONS:
These results suggest a new potential transmission path for carbapenemase gene spread through bacteria ingested by insects infesting humans.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Pediculus
/
Proteínas de Bactérias
/
Beta-Lactamases
/
Vestuário
Limite:
Animals
/
Humans
País como assunto:
Europa
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article