Identification of Genetic Modifiers of TDP-43: Inflammatory Activation of Astrocytes for Neuroinflammation.

Kim, Jae-Hong; Rahman, Md Habibur; Park, Donghwi; Jo, Myungjin; Kim, Hyung-Jun; Suk, Kyoungho

Kim, Jae-Hong; Rahman, Md Habibur; Park, Donghwi; Jo, Myungjin; Kim, Hyung-Jun; Suk, Kyoungho.

Afiliação

Kim JH; Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Rahman MH; BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Sciences, School of Medicine, Kyungpook National University, Daegu 412944, Korea.
Park D; Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.
Jo M; BK21 Plus KNU Biomedical Convergence Program, Department of Biomedical Sciences, School of Medicine, Kyungpook National University, Daegu 412944, Korea.
Kim HJ; Brain Science & Engineering Institute, Kyungpook National University, Daegu 41566, Korea.
Suk K; Department of Pharmacology, School of Medicine, Kyungpook National University, Daegu 41944, Korea.

Cells ; 10(3)2021 03 18.

Article em En | MEDLINE | ID: mdl-33803845

Assuntos

Esclerose Lateral Amiotrófica/metabolismo; Astrócitos/metabolismo; Proteínas de Ligação a DNA/metabolismo; Mutação/genética; Esclerose Lateral Amiotrófica/imunologia; Demência Frontotemporal/genética; Demência Frontotemporal/metabolismo; Humanos; Inflamação/metabolismo; Neuroglia/metabolismo

Palavras-chave

TDP-43; amyotrophic lateral sclerosis; astrocyte; genetic interaction; glia; neuroinflammation

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Astrócitos / Proteínas de Ligação a DNA / Esclerose Lateral Amiotrófica / Mutação Tipo de estudo: Diagnostic_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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