Cytotoxic Activity of LLO Y406A Is Targeted to the Plasma Membrane of Cancer Urothelial Cells.

Resnik, Natasa; Tratnjek, Larisa; Kreft, Mateja Erdani; Kisovec, Matic; Aden, Sasa; Bedina Zavec, Apolonija; Anderluh, Gregor; Podobnik, Marjetka; Veranic, Peter

Resnik, Natasa; Tratnjek, Larisa; Kreft, Mateja Erdani; Kisovec, Matic; Aden, Sasa; Bedina Zavec, Apolonija; Anderluh, Gregor; Podobnik, Marjetka; Veranic, Peter.

Afiliação

Resnik N; Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Tratnjek L; Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Kreft ME; Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.
Kisovec M; Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Aden S; Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Bedina Zavec A; Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Anderluh G; Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Podobnik M; Department of Molecular Biology and Nanobiotechnology, National Institute of Chemistry, SI-1000 Ljubljana, Slovenia.
Veranic P; Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, SI-1000 Ljubljana, Slovenia.

Int J Mol Sci ; 22(7)2021 Mar 24.

Article em En | MEDLINE | ID: mdl-33805017

Assuntos

Antineoplásicos/toxicidade; Toxinas Bacterianas/toxicidade; Membrana Celular/efeitos dos fármacos; Proteínas de Choque Térmico/toxicidade; Proteínas Hemolisinas/toxicidade; Neoplasias da Bexiga Urinária/metabolismo; Urotélio/efeitos dos fármacos; Animais; Toxinas Bacterianas/genética; Cálcio/metabolismo; Linhagem Celular Tumoral; Membrana Celular/metabolismo; Células Cultivadas; Endossomos/efeitos dos fármacos; Endossomos/metabolismo; Proteínas de Choque Térmico/genética; Proteínas Hemolisinas/genética; Humanos; Mutação; Suínos; Urotélio/metabolismo

Palavras-chave

bladder cancer; blebbing; calcium influx; cancer urothelial cells; cytolysin; cytotoxicity; listeriolysin O; normal urothelial cells; pore-forming toxin

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Toxinas Bacterianas / Neoplasias da Bexiga Urinária / Membrana Celular / Urotélio / Proteínas de Choque Térmico / Proteínas Hemolisinas / Antineoplásicos Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google