In Vitro Anticancer Potential of <i>Jasione montana</i> and Its Main Components against Human Amelanotic Melanoma Cells.

Juszczak, Aleksandra Maria; Czarnomysy, Robert; Strawa, Jakub Wladyslaw; Zovko Koncic, Marijana; Bielawski, Krzysztof; Tomczyk, Michal

In Vitro Anticancer Potential of Jasione montana and Its Main Components against Human Amelanotic Melanoma Cells.

Juszczak, Aleksandra Maria; Czarnomysy, Robert; Strawa, Jakub Wladyslaw; Zovko Koncic, Marijana; Bielawski, Krzysztof; Tomczyk, Michal.

Afiliação

Juszczak AM; Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bialystok, ul. Mickiewicza 2a, 15-230 Bialystok, Poland.
Czarnomysy R; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bialystok, ul. Kilinskiego 1, 15-089 Bialystok, Poland.
Strawa JW; Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bialystok, ul. Mickiewicza 2a, 15-230 Bialystok, Poland.
Zovko Koncic M; Department of Pharmacognosy, Faculty of Pharmacy and Biochemistry, University of Zagreb, Marulicev trg 20/II, 10000 Zagreb, Croatia.
Bielawski K; Department of Synthesis and Technology of Drugs, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bialystok, ul. Kilinskiego 1, 15-089 Bialystok, Poland.
Tomczyk M; Department of Pharmacognosy, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical University of Bialystok, ul. Mickiewicza 2a, 15-230 Bialystok, Poland.

Int J Mol Sci ; 22(7)2021 Mar 25.

Article em En | MEDLINE | ID: mdl-33805898

Assuntos

Antineoplásicos Fitogênicos/farmacologia; Campanulaceae/química; Flavonoides/farmacologia; Luteolina/química; Melanoma/patologia; Extratos Vegetais/farmacologia; Neoplasias Cutâneas/patologia; Apoptose; Autofagia; Caspase 3/metabolismo; Linhagem Celular Tumoral; Cromatografia Líquida; Dano ao DNA; Ativação Enzimática; Fibroblastos/efeitos dos fármacos; Humanos; Concentração Inibidora 50; Melanoma/tratamento farmacológico; Potencial da Membrana Mitocondrial; Compostos Fitoquímicos/farmacologia; Polifenóis/farmacologia; Neoplasias Cutâneas/tratamento farmacológico; Espectrometria de Massas por Ionização por Electrospray; Melanoma Maligno Cutâneo

Palavras-chave

Campanulaceae; Jasione montana; fibroblasts; flavonoids; luteolin derivatives; melanoma

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Cutâneas / Flavonoides / Extratos Vegetais / Campanulaceae / Luteolina / Melanoma / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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