Your browser doesn't support javascript.
loading
Discovery of a rare GKAP1-NTRK2 fusion in a pediatric low-grade glioma, leading to targeted treatment with TRK-inhibitor larotrectinib.
Deland, Lily; Keane, Simon; Olsson Bontell, Thomas; Sjögren, Helene; Fagman, Henrik; Øra, Ingrid; De La Cuesta, Esther; Tisell, Magnus; Nilsson, Jonas A; Ejeskär, Katarina; Sabel, Magnus; Abel, Frida.
Afiliação
  • Deland L; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Keane S; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Olsson Bontell T; Translational Medicine, School of Health Sciences, University of Skövde, Skövde, Sweden.
  • Sjögren H; Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Fagman H; Department of Physiology, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Øra I; Department of Clinical Genetics and Genomics, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • De La Cuesta E; Department of Clinical Pathology, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Tisell M; Department of Clinical Sciences, Lund University Hospital, Lund, Sweden.
  • Nilsson JA; HOPE/ITCC Phase I/II Trial Unit, Pediatric Oncology, Karolinska Hospital, Stockholm, Sweden.
  • Ejeskär K; Pharmaceuticals, Global Medical Affairs - Oncology, Bayer U.S., Whippany, USA.
  • Sabel M; Department of Clinical Neuroscience and Rehabilitation, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Abel F; Sahlgrenska Cancer Center, Department of Laboratory Medicine Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Cancer Biol Ther ; 22(3): 184-195, 2021 03 04.
Article em En | MEDLINE | ID: mdl-33820494

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Neoplasias Encefálicas / Proteínas de Fusão Oncogênica / Inibidores de Proteínas Quinases / Glioma Tipo de estudo: Prognostic_studies Limite: Child / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Pirimidinas / Neoplasias Encefálicas / Proteínas de Fusão Oncogênica / Inibidores de Proteínas Quinases / Glioma Tipo de estudo: Prognostic_studies Limite: Child / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article