HBV/Pregenomic RNA Increases the Stemness and Promotes the Development of HBV-Related HCC Through Reciprocal Regulation With Insulin-Like Growth Factor 2 mRNA-Binding Protein 3.

Ding, Wen-Bin; Wang, Meng-Chao; Yu, Jian; Huang, Gang; Sun, Da-Peng; Liu, Lei; Zhang, Jia-Ning; Yang, Yuan; Liu, Hui; Zhou, Wei-Ping; Yang, Fu; Yuan, Sheng-Xian

Ding, Wen-Bin; Wang, Meng-Chao; Yu, Jian; Huang, Gang; Sun, Da-Peng; Liu, Lei; Zhang, Jia-Ning; Yang, Yuan; Liu, Hui; Zhou, Wei-Ping; Yang, Fu; Yuan, Sheng-Xian.

Afiliação

Ding WB; The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Wang MC; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, China.
Yu J; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, China.
Huang G; The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Sun DP; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, China.
Liu L; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, China.
Zhang JN; The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Yang Y; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, China.
Liu H; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, China.
Zhou WP; The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Yang F; Key Laboratory of Signaling Regulation and Targeting Therapy of Liver Cancer (SMMU), Ministry of Education, Shanghai, China.
Yuan SX; Shanghai Key Laboratory of Hepatobiliary Tumor Biology (EHBH), Shanghai, China.

Hepatology ; 74(3): 1480-1495, 2021 09.

Article em En | MEDLINE | ID: mdl-33825218

Assuntos

Carcinoma Hepatocelular/virologia; Vírus da Hepatite B/genética; Neoplasias Hepáticas/virologia; RNA Viral/genética; Proteínas de Ligação a RNA/genética; Antivirais/uso terapêutico; Carcinoma Hepatocelular/genética; Linhagem Celular Tumoral; Proliferação de Células/genética; DNA Viral/metabolismo; Feminino; Técnicas de Silenciamento de Genes; Células HEK293; Células Hep G2; Hepatite B Crônica/complicações; Hepatite B Crônica/tratamento farmacológico; Hepatite B Crônica/virologia; Humanos; Neoplasias Hepáticas/genética; Masculino; Pessoa de Meia-Idade; Células-Tronco Neoplásicas; Prognóstico; Processamento Pós-Transcricional do RNA; RNA Viral/metabolismo; Proteínas de Ligação a RNA/metabolismo

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA Viral / Vírus da Hepatite B / Proteínas de Ligação a RNA / Carcinoma Hepatocelular / Neoplasias Hepáticas Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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