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First-in-human evaluation of the novel mitochondrial complex I inhibitor ASP4132 for treatment of cancer.
Janku, Filip; LoRusso, Patricia; Mansfield, Aaron S; Nanda, Rita; Spira, Alexander; Wang, Tianli; Melhem-Bertrandt, Amal; Sugg, Jennifer; Ball, Howard A.
Afiliação
  • Janku F; Investigational Cancer Therapeutics (Phase I Clinical Trials Program), The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Box 0455, Houston, TX, 77030, USA. FJanku@mdanderson.org.
  • LoRusso P; Yale Cancer Center, Yale University, New Haven, CT, USA.
  • Mansfield AS; Division of Medical Oncology, Mayo Clinic, Rochester, MN, USA.
  • Nanda R; University of Chicago, Chicago, IL, USA.
  • Spira A; US Oncology, Fairfax, VA, USA.
  • Wang T; GlaxoSmithKline plc, Waltham, MA, USA.
  • Melhem-Bertrandt A; Astellas Pharma US, Inc, Northbrook, IL, USA.
  • Sugg J; Astellas Pharma US, Inc, Northbrook, IL, USA.
  • Ball HA; Ball Pharma Consulting, LLC, Chicago, IL, USA.
Invest New Drugs ; 39(5): 1348-1356, 2021 10.
Article em En | MEDLINE | ID: mdl-33830407
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Piridinas / Complexo I de Transporte de Elétrons / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Piperazinas / Piridinas / Complexo I de Transporte de Elétrons / Neoplasias / Antineoplásicos Tipo de estudo: Clinical_trials Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article