Disruption of the MSL complex inhibits tumour maintenance by exacerbating chromosomal instability.

Monserrat, Josep; Morales Torres, Cristina; Richardson, Louise; Wilson, Thomas Stuart; Patel, Harshil; Domart, Marie-Charlotte; Horswell, Stuart; Song, Ok-Ryul; Jiang, Ming; Crawford, Margaret; Bui, Minh; Dalal, Yamini; Scaffidi, Paola

Monserrat, Josep; Morales Torres, Cristina; Richardson, Louise; Wilson, Thomas Stuart; Patel, Harshil; Domart, Marie-Charlotte; Horswell, Stuart; Song, Ok-Ryul; Jiang, Ming; Crawford, Margaret; Bui, Minh; Dalal, Yamini; Scaffidi, Paola.

Afiliação

Monserrat J; Cancer Epigenetics Laboratory, Francis Crick Institute, London, UK.
Morales Torres C; Cancer Epigenetics Laboratory, Francis Crick Institute, London, UK.
Richardson L; Cancer Epigenetics Laboratory, Francis Crick Institute, London, UK.
Wilson TS; Cancer Epigenetics Laboratory, Francis Crick Institute, London, UK.
Patel H; Bioinformatics and Biostatistics, Francis Crick Institute, London, UK.
Domart MC; Electron Microscopy, Francis Crick Institute, London, UK.
Horswell S; Bioinformatics and Biostatistics, Francis Crick Institute, London, UK.
Song OR; High Throughput Screening, Francis Crick Institute, London, UK.
Jiang M; High Throughput Screening, Francis Crick Institute, London, UK.
Crawford M; Advanced Sequencing, Francis Crick Institute, London, UK.
Bui M; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Dalal Y; Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Scaffidi P; Cancer Epigenetics Laboratory, Francis Crick Institute, London, UK. Paola.Scaffidi@crick.ac.uk.

Nat Cell Biol ; 23(4): 401-412, 2021 04.

Article em En | MEDLINE | ID: mdl-33837287

Assuntos

Proliferação de Células/genética; Instabilidade Cromossômica/genética; Complexos Multiproteicos/genética; Neoplasias/genética; Animais; Linhagem Celular Tumoral; Reprogramação Celular/genética; Proteínas Cromossômicas não Histona/genética; Proteínas de Ligação a DNA/genética; Xenoenxertos; Histona Acetiltransferases/genética; Humanos; Camundongos; Neoplasias/patologia; Fatores de Transcrição/genética; Proteína Supressora de Tumor p53/genética; Ubiquitina-Proteína Ligases/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Instabilidade Cromossômica / Complexos Multiproteicos / Proliferação de Células / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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