Trex2 responds to damaged replication forks in diverse ways.
Mol Cell Oncol
; 8(2): 1881394, 2021.
Article
em En
| MEDLINE
| ID: mdl-33860084
ABSTRACT
Three prime Repair Exonuclease 2 (Trex2) alters replication fork (RF) stability and mutation levels in cells defective for homologous recombination (HR). Trex2 has multiple functions that can either cause or supress RF instability in cells with different HR-defects. Why does Trex2 have such diverse effects on RF maintenance?
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MEDLINE
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En
Ano de publicação:
2021
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Article