Seeing the forest for the trees-single-cell atlases link CD8<sup>+</sup> T cells and macrophages to disease progression and treatment response in kidney cancer.

Koh, Mei Yee; Sayegh, Nicolas; Agarwal, Neeraj

Seeing the forest for the trees-single-cell atlases link CD8⁺ T cells and macrophages to disease progression and treatment response in kidney cancer.

Koh, Mei Yee; Sayegh, Nicolas; Agarwal, Neeraj.

Afiliação

Koh MY; Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112; Department of Pharmacology and Toxicology, University of Utah, 30S 2000E, Salt Lake City, UT 84112.
Sayegh N; Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112.
Agarwal N; Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope Drive, Salt Lake City, UT 84112. Electronic address: neeraj.agarwal@hci.utah.edu.

Cancer Cell ; 39(5): 594-596, 2021 05 10.

Article em En | MEDLINE | ID: mdl-33861995

Assuntos

Carcinoma de Células Renais; Neoplasias Renais; Linfócitos T CD8-Positivos; Carcinoma de Células Renais/genética; Carcinoma de Células Renais/terapia; Progressão da Doença; Humanos; Neoplasias Renais/genética; Neoplasias Renais/terapia; Macrófagos

Palavras-chave

CD8(+) T cells; biomarkers; immune checkpoint blockade; kidney cancer; macrophage; single-cell RNA sequencing

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Carcinoma de Células Renais / Neoplasias Renais Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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