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Autoimmune polyendocrine syndrome type 3, characterized by autoimmune thyroid disease, type 1 diabetes mellitus, and isolated ACTH deficiency, developed during adjuvant nivolumab treatment.
Takata, Mayumi; Nomura, Motoo; Yamamura, Kentaro; Muto, Manabu; Komori, Takaya; Otsuka, Atsushi; Kabashima, Kenji.
Afiliação
  • Takata M; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Nomura M; Department of Medical Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Yamamura K; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Muto M; Department of Dermato-Oncology Dermatology, National Hospital Organization Kagoshima Medical Center, Kagoshima, Japan.
  • Komori T; Department of Medical Oncology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Otsuka A; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
  • Kabashima K; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Asia Pac J Clin Oncol ; 18(4): 481-482, 2022 Aug.
Article em En | MEDLINE | ID: mdl-33870636
ABSTRACT
Autoimmune polyendocrine syndrome (APS) is one of the life-threatening immune-related adverse events (irAEs). We firstly report a case of APS induced by adjuvant nivolumab therapy. Clinicians should be aware of the potential risks of developing severe irAEs when applying adjuvant immunotherapy.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças da Glândula Tireoide / Poliendocrinopatias Autoimunes / Diabetes Mellitus Tipo 1 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doenças da Glândula Tireoide / Poliendocrinopatias Autoimunes / Diabetes Mellitus Tipo 1 Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article