KIF18A knockdown reduces proliferation, migration, invasion and enhances radiosensitivity of esophageal cancer.

Qian, Lu-Xi; Cao, Xiang; Du, Ming-Yu; Ma, Cheng-Xian; Zhu, Hong-Ming; Peng, Yi; Hu, Xin-Yu; He, Xia; Yin, Li

Qian, Lu-Xi; Cao, Xiang; Du, Ming-Yu; Ma, Cheng-Xian; Zhu, Hong-Ming; Peng, Yi; Hu, Xin-Yu; He, Xia; Yin, Li.

Afiliação

Qian LX; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
Cao X; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
Du MY; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
Ma CX; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
Zhu HM; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
Peng Y; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
Hu XY; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China.
He X; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China; Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Collaborative Innovation Center fo
Yin L; Department of Radiation Oncology, The Affiliated Cancer Hospital of Nanjing Medical University & Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research, Nanjing, 210000, Jiangsu, China. Electronic address: yinli_2012@126.com.

Biochem Biophys Res Commun ; 557: 192-198, 2021 06 11.

Article em En | MEDLINE | ID: mdl-33872988

Assuntos

Movimento Celular/genética; Proliferação de Células/genética; Neoplasias Esofágicas/metabolismo; Cinesinas/metabolismo; Invasividade Neoplásica/genética; Tolerância a Radiação/genética; Linhagem Celular Tumoral; Movimento Celular/efeitos da radiação; Proliferação de Células/efeitos da radiação; Neoplasias Esofágicas/genética; Neoplasias Esofágicas/patologia; Perfilação da Expressão Gênica; Regulação Neoplásica da Expressão Gênica/genética; Técnicas de Silenciamento de Genes; Humanos; Cinesinas/genética; Prognóstico; Proteínas de Ligação a RNA/genética; Proteínas de Ligação a RNA/metabolismo; Reação em Cadeia da Polimerase em Tempo Real; Regulação para Cima

Palavras-chave

Esophageal cancer; IGF2BP3; KIF18A; Proliferation; Radiosensitivity; mRNA stability

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tolerância a Radiação / Neoplasias Esofágicas / Movimento Celular / Cinesinas / Proliferação de Células / Invasividade Neoplásica Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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