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Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer.
Sadras, Teresa; Martin, Mickaël; Kume, Kohei; Robinson, Mark E; Saravanakumar, Supraja; Lenz, Gal; Chen, Zhengshan; Song, Joo Y; Siddiqi, Tanya; Oksa, Laura; Knapp, Anne Marie; Cutler, Jevon; Cosgun, Kadriye Nehir; Klemm, Lars; Ecker, Veronika; Winchester, Janet; Ghergus, Dana; Soulas-Sprauel, Pauline; Kiefer, Friedemann; Heisterkamp, Nora; Pandey, Akhilesh; Ngo, Vu; Wang, Lili; Jumaa, Hassan; Buchner, Maike; Ruland, Jürgen; Chan, Wing-Chung; Meffre, Eric; Martin, Thierry; Müschen, Markus.
Afiliação
  • Sadras T; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.
  • Martin M; CNRS UPR 3572 "Immunopathology and Therapeutic Chemistry," Institute of Molecular and Cellular Biology (IBMC), Strasbourg, France; Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg, France.
  • Kume K; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA.
  • Robinson ME; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA.
  • Saravanakumar S; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Lenz G; Department of Cancer Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Chen Z; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Song JY; Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Siddiqi T; Department of Hematology and Hematopoietic Cell Transplantation, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Oksa L; Tampere Center for Child Health Research, Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
  • Knapp AM; CNRS UPR 3572 "Immunopathology and Therapeutic Chemistry," Institute of Molecular and Cellular Biology (IBMC), Strasbourg, France.
  • Cutler J; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Cosgun KN; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA.
  • Klemm L; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA.
  • Ecker V; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA; Institute of Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Klinikum rechts der Isar, 81675 Munich, Germany.
  • Winchester J; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Ghergus D; Department of Clinical Hematology, Hospices Civils de Lyon, Lyon, France.
  • Soulas-Sprauel P; CNRS UPR 3572 "Immunopathology and Therapeutic Chemistry," Institute of Molecular and Cellular Biology (IBMC), Strasbourg, France; Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg, France.
  • Kiefer F; Mammalian Cell Signaling Laboratory, Department of Vascular Cell Biology, Max Planck Institute for Molecular Biomedicine, Münster, Germany.
  • Heisterkamp N; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Pandey A; Department of Biological Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
  • Ngo V; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Wang L; Department of Systems Biology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Jumaa H; Department of Immunology, University of Ulm, Ulm, Germany.
  • Buchner M; Institute of Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Klinikum rechts der Isar, 81675 Munich, Germany.
  • Ruland J; Institute of Clinical Chemistry and Pathobiochemistry, Technical University of Munich, Klinikum rechts der Isar, 81675 Munich, Germany.
  • Chan WC; Department of Pathology, City of Hope Comprehensive Cancer Center, Duarte, CA, USA.
  • Meffre E; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. Electronic address: eric.meffre@yale.edu.
  • Martin T; CNRS UPR 3572 "Immunopathology and Therapeutic Chemistry," Institute of Molecular and Cellular Biology (IBMC), Strasbourg, France; Department of Clinical Immunology, Strasbourg University Hospital, Strasbourg, France. Electronic address: thierry.martin@chru-strasbourg.fr.
  • Müschen M; Center of Molecular and Cellular Oncology, Yale Cancer Center, Yale School of Medicine, New Haven, CT, USA; Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA. Electronic address: markus.muschen@yale.edu.
Mol Cell ; 81(10): 2094-2111.e9, 2021 05 20.
Article em En | MEDLINE | ID: mdl-33878293
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoimunidade / Proteína-Tirosina Quinase ZAP-70 / Quinase Syk / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Autoimunidade / Proteína-Tirosina Quinase ZAP-70 / Quinase Syk / Neoplasias Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article