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Ultrasound-Enhanced Self-Exciting Photodynamic Therapy Based on Hypocrellin B.
Ding, Ying; Liu, Weimin; Wu, Jiasheng; Zheng, Xiuli; Ge, Jiechao; Ren, Haohui; Zhang, Wenjun; Lee, Chun-Sing; Wang, Pengfei.
Afiliação
  • Ding Y; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
  • Liu W; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
  • Wu J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
  • Zheng X; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
  • Ge J; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
  • Ren H; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
  • Zhang W; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
  • Lee CS; School of Future Technology, University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
  • Wang P; Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Chem Asian J ; 16(10): 1221-1224, 2021 May 17.
Article em En | MEDLINE | ID: mdl-33881805
ABSTRACT
Peroxalate CL as an energy source to excite photosensitizers has attracted tremendous attention in photodynamic therapy (PDT). In this work, peroxyoxalate CPPO and hypocrellin B (HB)-based nanoparticles (CBNPs) for ultrasound (US)-enhanced self-exciting PDT were designed and prepared. CBNPs showed an excellent therapeutic effect against cancer cells with the assistance of US. This US-enhanced-chemiluminescence system avoids the dependence on external light and provides an example for inspiring more effective and precise strategies for cancer treatment.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Perileno / Fotoquimioterapia / Quinonas / Fármacos Fotossensibilizantes / Ondas Ultrassônicas / Estruturas Metalorgânicas / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Perileno / Fotoquimioterapia / Quinonas / Fármacos Fotossensibilizantes / Ondas Ultrassônicas / Estruturas Metalorgânicas / Antineoplásicos Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article