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Targeting Runt-Related Transcription Factor 1 Prevents Pulmonary Fibrosis and Reduces Expression of Severe Acute Respiratory Syndrome Coronavirus 2 Host Mediators.
O'Hare, Michael; Amarnani, Dhanesh; Whitmore, Hannah A B; An, Miranda; Marino, Claudia; Ramos, Leslie; Delgado-Tirado, Santiago; Hu, Xinyao; Chmielewska, Natalia; Chandrahas, Anita; Fitzek, Antonia; Heinrich, Fabian; Steurer, Stefan; Ondruschka, Benjamin; Glatzel, Markus; Krasemann, Susanne; Sepulveda-Falla, Diego; Lagares, David; Pedron, Julien; Bushweller, John H; Liu, Paul; Arboleda-Velasquez, Joseph F; Kim, Leo A.
Afiliação
  • O'Hare M; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Amarnani D; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Whitmore HAB; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • An M; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Marino C; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Ramos L; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Delgado-Tirado S; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Hu X; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Chmielewska N; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Chandrahas A; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts.
  • Fitzek A; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Heinrich F; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Steurer S; Institute of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Ondruschka B; Institute of Legal Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Glatzel M; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Krasemann S; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Sepulveda-Falla D; Institute of Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
  • Lagares D; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
  • Pedron J; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia.
  • Bushweller JH; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia.
  • Liu P; National Institutes of Health, National Human Genome Research Institute, Bethesda, Maryland.
  • Arboleda-Velasquez JF; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts. Electronic address: joseph_arboleda@meei.harvard.edu.
  • Kim LA; Schepens Eye Research Institute of Mass Eye and Ear, Boston, Massachusetts, and the Department of Ophthalmology at Harvard Medical School, Boston, Massachusetts. Electronic address: leo_kim@meei.harvard.edu.
Am J Pathol ; 191(7): 1193-1208, 2021 07.
Article em En | MEDLINE | ID: mdl-33894177
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Furina / Subunidade alfa 2 de Fator de Ligação ao Core / Enzima de Conversão de Angiotensina 2 / COVID-19 / Pulmão Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fibrose Pulmonar / Furina / Subunidade alfa 2 de Fator de Ligação ao Core / Enzima de Conversão de Angiotensina 2 / COVID-19 / Pulmão Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article