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Structure-Guided Development of Potent Benzoylurea Inhibitors of BCL-XL and BCL-2.
Roy, Michael J; Vom, Amelia; Okamoto, Toru; Smith, Brian J; Birkinshaw, Richard W; Yang, Hong; Abdo, Houda; White, Christine A; Segal, David; Huang, David C S; Baell, Jonathan B; Colman, Peter M; Czabotar, Peter E; Lessene, Guillaume.
Afiliação
  • Roy MJ; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • Vom A; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
  • Okamoto T; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • Smith BJ; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
  • Birkinshaw RW; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • Yang H; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
  • Abdo H; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • White CA; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
  • Segal D; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • Huang DCS; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
  • Baell JB; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • Colman PM; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
  • Czabotar PE; The Walter and Eliza Hall Institute of Medical Research, 1G Royal Parade, Parkville, VIC 3052, Australia.
  • Lessene G; Department of Medical Biology, The University of Melbourne, Parkville, VIC 3050, Australia.
J Med Chem ; 64(9): 5447-5469, 2021 05 13.
Article em En | MEDLINE | ID: mdl-33904752
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína bcl-X / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ureia / Proteínas Proto-Oncogênicas c-bcl-2 / Proteína bcl-X / Antineoplásicos Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article