Carbohydrate based meningococcal vaccines: past and present overview.
Glycoconj J
; 38(4): 401-409, 2021 08.
Article
em En
| MEDLINE
| ID: mdl-33905086
ABSTRACT
Neisseria meningitidis is a major cause of bacterial meningitidis worldwide. Children less than five years and adolescents are particularly affected. Nearly all invasive strains are surrounded by a polysaccharide capsule, based on which, 12 N. meningitidis serogroups are differentiated. Six of them, A, B, C, W, X, and Y, cause the vast majority of infections in humans. Mono- and multi-valent carbohydrate-based vaccines against meningococcal infections have been licensed or are currently in clinical development. In this mini-review, an overview of the past and present approaches for producing meningococcal glycoconjugate vaccines is provided.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Glicoconjugados
/
Vacinas Meningocócicas
/
Infecções Meningocócicas
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article