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Hsp90 and its co-chaperone Sti1 control TDP-43 misfolding and toxicity.
Lin, Lilian Tsai-Wei; Razzaq, Abdul; Di Gregorio, Sonja E; Hong, Soojie; Charles, Brendan; Lopes, Marilene H; Beraldo, Flavio; Prado, Vania F; Prado, Marco A M; Duennwald, Martin L.
Afiliação
  • Lin LT; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Razzaq A; Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Di Gregorio SE; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Hong S; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Charles B; Department of Pathology and Laboratory Medicine, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Lopes MH; Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Beraldo F; Department of Anatomy & Cell Biology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Prado VF; Department of Cell and Developmental Biology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
  • Prado MAM; Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
  • Duennwald ML; Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada.
FASEB J ; 35(5): e21594, 2021 05.
Article em En | MEDLINE | ID: mdl-33908654

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Dobramento de Proteína / Apoptose / Proteínas de Choque Térmico HSP90 / Proteínas de Ligação a DNA / Proteinopatias TDP-43 / Proteínas de Choque Térmico Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Saccharomyces cerevisiae / Dobramento de Proteína / Apoptose / Proteínas de Choque Térmico HSP90 / Proteínas de Ligação a DNA / Proteinopatias TDP-43 / Proteínas de Choque Térmico Tipo de estudo: Etiology_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article