Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model.

Thacker, Vivek V; Sharma, Kunal; Dhar, Neeraj; Mancini, Gian-Filippo; Sordet-Dessimoz, Jessica; McKinney, John D

Thacker, Vivek V; Sharma, Kunal; Dhar, Neeraj; Mancini, Gian-Filippo; Sordet-Dessimoz, Jessica; McKinney, John D.

Afiliação

Thacker VV; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Sharma K; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Dhar N; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Mancini GF; Histology Core Facility, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
Sordet-Dessimoz J; Histology Core Facility, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
McKinney JD; Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.

EMBO Rep ; 22(6): e52744, 2021 06 04.

Article em En | MEDLINE | ID: mdl-33908688

Assuntos

COVID-19; SARS-CoV-2; Síndrome da Liberação de Citocina; Células Endoteliais; Humanos; Pulmão

Palavras-chave

COVID-19; alveolar models; interleukin-6; organ-on-chip; vasculitis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

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PubMed Links

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: SARS-CoV-2 / COVID-19 Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article