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Design, synthesis, and molecular simulation studies of N-phenyltetrahydroquinazolinones as protoporphyrinogen IX oxidase inhibitors.
Liang, Lu; Yu, Shuyi; Li, Qian; Wang, Xia; Wang, Dawei; Xi, Zhen.
Afiliação
  • Liang L; State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, and Department of Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai University, Tianjin 300071, PR China.
  • Yu S; State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, and Department of Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai University, Tianjin 300071, PR China.
  • Li Q; State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, and Department of Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai University, Tianjin 300071, PR China.
  • Wang X; State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, and Department of Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai University, Tianjin 300071, PR China.
  • Wang D; State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, and Department of Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai University, Tianjin 300071, PR China.
  • Xi Z; State Key Laboratory of Elemento-Organic Chemistry, National Pesticide Engineering Research Center, and Department of Chemical Biology, Collaborative Innovation Center of Chemical Science and Engineering, College of Chemistry, Nankai University, Tianjin 300071, PR China. Electronic address: zhenxi@n
Bioorg Med Chem ; 39: 116165, 2021 06 01.
Article em En | MEDLINE | ID: mdl-33915477

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores Enzimáticos / Protoporfirinogênio Oxidase / Quinazolinonas Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Inibidores Enzimáticos / Protoporfirinogênio Oxidase / Quinazolinonas Idioma: En Ano de publicação: 2021 Tipo de documento: Article