Artesunate-induced ATG5-related autophagy enhances the cytotoxicity of NK92 cells on endometrial cancer cells via interactions between CD155 and CD226/TIGIT.

Zhang, Jie; Zhou, Long; Xiang, Jiang-Dong; Jin, Chun-Sheng; Li, Ming-Qing; He, Yin-Yan

Zhang, Jie; Zhou, Long; Xiang, Jiang-Dong; Jin, Chun-Sheng; Li, Ming-Qing; He, Yin-Yan.

Afiliação

Zhang J; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, People's Republic of China.
Zhou L; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, People's Republic of China.
Xiang JD; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, People's Republic of China.
Jin CS; Department of Biomedicine, Division of Medical Chemistry and Cell Biology, University of Gothenburg, Sweden.
Li MQ; Laboratory for Reproductive Immunology, NHC Key Lab of Reproduction Regulation (Shanghai Institute of Planned Parenthood Research), Hospital of Obstetrics and Gynecology, Shanghai Medical School, Fudan University, Shanghai 200080, People's Republic of China; Shanghai Key Laboratory of Female Reprodu
He YY; Department of Obstetrics and Gynecology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, No.100, Haining Road, Shanghai 200080, People's Republic of China; Department of Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medic

Int Immunopharmacol ; 97: 107705, 2021 Aug.

Article em En | MEDLINE | ID: mdl-33933849

Assuntos

Artesunato/farmacologia; Neoplasias do Endométrio/tratamento farmacológico; Células Matadoras Naturais/imunologia; Artesunato/uso terapêutico; Autofagia/efeitos dos fármacos; Autofagia/imunologia; Proteína 5 Relacionada à Autofagia/genética; Proteína 5 Relacionada à Autofagia/metabolismo; Linhagem Celular Tumoral; Técnicas de Cocultura; Regulação para Baixo/efeitos dos fármacos; Ensaios de Seleção de Medicamentos Antitumorais; Neoplasias do Endométrio/imunologia; Neoplasias do Endométrio/patologia; Feminino; Regulação Neoplásica da Expressão Gênica/efeitos dos fármacos; Técnicas de Silenciamento de Genes; Humanos; Receptores Imunológicos/metabolismo; Receptores Virais/metabolismo; Transdução de Sinais/efeitos dos fármacos; Transdução de Sinais/imunologia

Palavras-chave

Artesunate; Autophagy; CD155; Endometrial cancer; NK cell

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células Matadoras Naturais / Neoplasias do Endométrio / Artesunato Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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