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Morin attenuates pyroptosis of nucleus pulposus cells and ameliorates intervertebral disc degeneration via inhibition of the TXNIP/NLRP3/Caspase-1/IL-1ß signaling pathway.
Zhou, Yifan; Chen, Zhiqian; Yang, Xiao; Cao, Xiankun; Liang, Zhihao; Ma, Hui; Zhao, Jie.
Afiliação
  • Zhou Y; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Chen Z; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Yang X; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Cao X; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Liang Z; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Ma H; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.
  • Zhao J; Shanghai Key Laboratory of Orthopaedic Implants, Department of Orthopaedic Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China. Electronic address: profzhaojie@126.com.
Biochem Biophys Res Commun ; 559: 106-112, 2021 06 25.
Article em En | MEDLINE | ID: mdl-33933989
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flavonoides / Transdução de Sinais / Degeneração do Disco Intervertebral / Piroptose / Núcleo Pulposo Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Flavonoides / Transdução de Sinais / Degeneração do Disco Intervertebral / Piroptose / Núcleo Pulposo Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article