Hydro-alcoholic extract of <i>Morus nigra</i> reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and <i>in silico</i> analysis.

Momeni, Hamid; Salehi, Ashraf; Absalan, Abdorrahim; Akbari, Mehran

Hydro-alcoholic extract of Morus nigra reduces fasting blood glucose and HbA1c% in diabetic patients, probably via competitive and allosteric interaction with alpha-glucosidase enzyme; a clinical trial and in silico analysis.

Momeni, Hamid; Salehi, Ashraf; Absalan, Abdorrahim; Akbari, Mehran.

Afiliação

Momeni H; Department of Nursing, Khomein University of Medical Sciences, Khomein, Iran.
Salehi A; Department of Nursing, Khomein University of Medical Sciences, Khomein, Iran.
Absalan A; Department of Medical Laboratory Sciences, Khomein University of Medical Sciences, Khomein, Iran.
Akbari M; Department of Nursing, Khomein University of Medical Sciences, Khomein, Iran.

J Complement Integr Med ; 19(3): 763-769, 2022 Sep 01.

Article em En | MEDLINE | ID: mdl-33946137

Assuntos

Diabetes Mellitus; Morus; 1-Desoxinojirimicina/farmacologia; 1-Desoxinojirimicina/uso terapêutico; Glicemia/análise; Jejum; Glucosidases/análise; Hemoglobinas Glicadas; Humanos; Morus/química; Extratos Vegetais/análise; Extratos Vegetais/farmacologia; Extratos Vegetais/uso terapêutico; Folhas de Planta/química; Polímeros/análise; Água/análise; alfa-Glucosidases

Palavras-chave

Morus nigra; diabetes; glucosidase; hemoglobin A1c; virtual analysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Morus / Diabetes Mellitus Tipo de estudo: Clinical_trials Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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