Presence of donor specific HLA class 2 antibodies (DSA class 2) is associated with development of graft fibrosis more than 10 years after liver transplantation-a retrospective single center study.

Sultani, Bejan; Marget, Matthias; Briem-Richter, Andrea; Herrmann, Jochen; Meisner, Sebastian; Grabhorn, Enke Freya; Ozga, Ann-Kathrin; Weidemann, Sören; Herden, Uta; Fischer, Lutz; Sterneck, Martina

Presence of donor specific HLA class 2 antibodies (DSA class 2) is associated with development of graft fibrosis more than 10 years after liver transplantation-a retrospective single center study.

Sultani, Bejan; Marget, Matthias; Briem-Richter, Andrea; Herrmann, Jochen; Meisner, Sebastian; Grabhorn, Enke Freya; Ozga, Ann-Kathrin; Weidemann, Sören; Herden, Uta; Fischer, Lutz; Sterneck, Martina.

Afiliação

Sultani B; Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Marget M; Institute of Transfusion Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Briem-Richter A; Department of Pediatric Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Herrmann J; Department of Pediatric Radiology, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Meisner S; Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Grabhorn EF; Department of Pediatric Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Ozga AK; Insitute of Medical Biometry, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Weidemann S; Department of Pathology, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Herden U; Department of Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Fischer L; Department of Visceral Transplantation, University Medical Center Hamburg Eppendorf, Hamburg, Germany.
Sterneck M; Department of Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany.

Clin Transplant ; 35(7): e14336, 2021 07.

Article em En | MEDLINE | ID: mdl-33949011

Assuntos

Transplante de Fígado; Adulto; Criança; Fibrose; Rejeição de Enxerto/etiologia; Sobrevivência de Enxerto; Antígenos HLA; Teste de Histocompatibilidade; Humanos; Isoanticorpos; Transplante de Fígado/efeitos adversos; Estudos Retrospectivos

Palavras-chave

fibrosis; liver disease: immune/inflammatory; rejection: antibodymediated (ABM)

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transplante de Fígado Tipo de estudo: Etiology_studies / Observational_studies / Risk_factors_studies Limite: Adult / Child / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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