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Ruthenium(II) complexes as bioorthogonal two-photon photosensitizers for tumour-specific photodynamic therapy against triple-negative breast cancer cells.
Lin, Mingwei; Zou, Shanshan; Liao, Xinxing; Chen, Yu; Luo, Diqing; Ji, Liangnian; Chao, Hui.
Afiliação
  • Lin M; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. ceschh@mail.sysu.edu.cn chenyu63@mail.sysu.edu.cn.
  • Zou S; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. ceschh@mail.sysu.edu.cn chenyu63@mail.sysu.edu.cn.
  • Liao X; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. ceschh@mail.sysu.edu.cn chenyu63@mail.sysu.edu.cn.
  • Chen Y; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. ceschh@mail.sysu.edu.cn chenyu63@mail.sysu.edu.cn.
  • Luo D; Department of Dermatology, The Eastern Division of the First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. luodq@mail.sysu.edu.cn.
  • Ji L; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. ceschh@mail.sysu.edu.cn chenyu63@mail.sysu.edu.cn.
  • Chao H; MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou, 510275, P. R. China. ceschh@mail.sysu.edu.cn chenyu63@mail.sysu.edu.cn.
Chem Commun (Camb) ; 57(36): 4408-4411, 2021 May 04.
Article em En | MEDLINE | ID: mdl-33949487
Herein, we developed the first Ru(ii) complex-based bioorthogonal two-photon photosensitizers. Through bioorthogonal labelling, they realize effective tumour-specific photodynamic therapy against triple-negative breast cancer cells.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Rutênio / Fármacos Fotossensibilizantes / Fótons / Complexos de Coordenação / Neoplasias de Mama Triplo Negativas / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fotoquimioterapia / Rutênio / Fármacos Fotossensibilizantes / Fótons / Complexos de Coordenação / Neoplasias de Mama Triplo Negativas / Antineoplásicos Limite: Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article