Identification of diagnostic markers and lipid dysregulation in oesophageal squamous cell carcinoma through lipidomic analysis and machine learning.

Yuan, Yuyao; Zhao, Zitong; Xue, Liyan; Wang, Guangxi; Song, Huajie; Pang, Ruifang; Zhou, Juntuo; Luo, Jianyuan; Song, Yongmei; Yin, Yuxin

Yuan, Yuyao; Zhao, Zitong; Xue, Liyan; Wang, Guangxi; Song, Huajie; Pang, Ruifang; Zhou, Juntuo; Luo, Jianyuan; Song, Yongmei; Yin, Yuxin.

Afiliação

Yuan Y; Department of Pathology, School of Basic Medical Sciences, Institute of Systems Biomedicine, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.
Zhao Z; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Xue L; Department of Pathology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Wang G; Department of Pathology, School of Basic Medical Sciences, Institute of Systems Biomedicine, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.
Song H; Department of Pathology, School of Basic Medical Sciences, Institute of Systems Biomedicine, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.
Pang R; Department of Pathology, School of Basic Medical Sciences, Institute of Systems Biomedicine, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.
Zhou J; Institute of Precision Medicine, Peking University Shenzhen Hospital, Shenzhen, China.
Luo J; Department of Pathology, School of Basic Medical Sciences, Institute of Systems Biomedicine, Peking-Tsinghua Center for Life Sciences, Peking University Health Science Center, Beijing, China.
Song Y; Department of Medical Genetics, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China.
Yin Y; State Key Laboratory of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. songym@cicams.ac.cn.

Br J Cancer ; 125(3): 351-357, 2021 08.

Article em En | MEDLINE | ID: mdl-33953345

Assuntos

Biomarcadores Tumorais/sangue; Biomarcadores Tumorais/genética; Neoplasias Esofágicas/diagnóstico; Carcinoma de Células Escamosas do Esôfago/diagnóstico; Perfilação da Expressão Gênica/métodos; Lipidômica/métodos; Idoso; Área Sob a Curva; Estudos de Casos e Controles; Detecção Precoce de Câncer; Neoplasias Esofágicas/sangue; Neoplasias Esofágicas/metabolismo; Carcinoma de Células Escamosas do Esôfago/sangue; Carcinoma de Células Escamosas do Esôfago/metabolismo; Feminino; Regulação Neoplásica da Expressão Gênica; Humanos; Aprendizado de Máquina; Masculino; Pessoa de Meia-Idade; Prognóstico; Curva ROC; Sensibilidade e Especificidade; Máquina de Vetores de Suporte

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Esofágicas / Biomarcadores Tumorais / Perfilação da Expressão Gênica / Carcinoma de Células Escamosas do Esôfago / Lipidômica Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Screening_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google