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Rituximab Treatment in Acute Disseminated Encephalomyelitis Associated with Salmonella Infection.
Kacmaz, Ebru; Bozan, Gurkan; Carman, Kursat Bora; Kilic, Omer; Arslanoglu, Mehmet Ozgur; Toprak, Ugur; Kavaz Tufan, Asli; Yarar, Coskun; Dinleyici, Ener Cagri.
Afiliação
  • Kacmaz E; Eskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, Turkey.
  • Bozan G; Eskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, Turkey.
  • Carman KB; Eskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Neurology, Eskisehir, Turkey.
  • Kilic O; Eskisehir Osmangazi University Faculty of Medicine, Pediatric Infectious Disease Unit, Eskisehir, Turkey.
  • Arslanoglu MO; Eskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, Turkey.
  • Toprak U; Eskisehir Osmangazi University Faculty of Medicine, Department of Radiology, Eskisehir, Turkey.
  • Kavaz Tufan A; Eskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Nephrology, Eskisehir, Turkey.
  • Yarar C; Eskisehir Osmangazi University Faculty of Medicine, Department of Pediatric Neurology, Eskisehir, Turkey.
  • Dinleyici EC; Eskisehir Osmangazi University Faculty of Medicine, Pediatric Intensive Care Unit, Eskisehir, Turkey.
Case Rep Pediatr ; 2021: 5570566, 2021.
Article em En | MEDLINE | ID: mdl-33954003
ABSTRACT
Acute disseminated encephalomyelitis (ADEM) is an inflammatory, demyelinating, and rapidly progressive disorder of the central nervous system. This condition is also known as postinfectious encephalomyelitis, and it is characterized by multifocal lesions in the brain and spinal cord with widespread neurological findings. High doses of intravenous (IV) methylprednisolone, intravenous immunoglobulin (IVIG), and plasma exchange (PLEX) treatments comprise the first-line therapy. There are limited pediatric case reports refractory to standard treatment. Here, we present the case of a 17-year-old girl diagnosed with ADEM associated with Salmonella infection, which was treated with rituximab.

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Ano de publicação: 2021 Tipo de documento: Article