The role of PKA/PP2B-mediated Drp1 phosphorylation and the subsequent EGFR inhibition in Cr(VI)-induced premature senescence.

Li, Siwen; Ma, Yu; Liang, Yuehui; Liang, Ningjuan; Ye, Shuzi; Xiao, Fang.

Afiliação

Li S; Xiangya School of Public Health, Central South University, Changsha 410078, PR China.
Ma Y; Xiangya School of Public Health, Central South University, Changsha 410078, PR China.
Liang Y; Xiangya School of Public Health, Central South University, Changsha 410078, PR China.
Liang N; Xiangya School of Public Health, Central South University, Changsha 410078, PR China.
Ye S; Xiangya School of Public Health, Central South University, Changsha 410078, PR China.
Xiao F; Xiangya School of Public Health, Central South University, Changsha 410078, PR China. Electronic address: fangxiao@csu.edu.cn.

Ecotoxicol Environ Saf ; 218: 112300, 2021 May 07.

Article em En | MEDLINE | ID: mdl-33971394

Palavras-chave

Dynamin-relatedprotein 1 (Drp1) phosphorylation; Hexavalent chromium [Cr(VI)]; L02 hepatocytes; Premature senescence; Protein kinase A (PKA)/protein phosphatase 2B (PP2B)

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article