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The genomic loci of specific human tRNA genes exhibit ageing-related DNA hypermethylation.
Acton, Richard J; Yuan, Wei; Gao, Fei; Xia, Yudong; Bourne, Emma; Wozniak, Eva; Bell, Jordana; Lillycrop, Karen; Wang, Jun; Dennison, Elaine; Harvey, Nicholas C; Mein, Charles A; Spector, Tim D; Hysi, Pirro G; Cooper, Cyrus; Bell, Christopher G.
Afiliação
  • Acton RJ; William Harvey Research Institute, Barts & The London School of Medicine and Dentistry, Charterhouse Square, Queen Mary University of London, London, UK.
  • Yuan W; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
  • Gao F; Human Development and Health, Institute of Developmental Sciences, University of Southampton, Southampton, UK.
  • Xia Y; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital, King's College London, London, UK.
  • Bourne E; Institute of Cancer Research, Sutton, UK.
  • Wozniak E; BGI-Shenzhen, Shenzhen, China.
  • Bell J; BGI-Shenzhen, Shenzhen, China.
  • Lillycrop K; Barts & The London Genome Centre, Blizard Institute, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Wang J; Barts & The London Genome Centre, Blizard Institute, Barts & The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
  • Dennison E; Department of Twin Research & Genetic Epidemiology, St Thomas Hospital, King's College London, London, UK.
  • Harvey NC; Human Development and Health, Institute of Developmental Sciences, University of Southampton, Southampton, UK.
  • Mein CA; Shenzhen Digital Life Institute, Shenzhen, Guangdong, China.
  • Spector TD; iCarbonX, Zhuhai, Guangdong, China.
  • Hysi PG; State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Taipa, Macau, China.
  • Cooper C; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
  • Bell CG; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UK.
Nat Commun ; 12(1): 2655, 2021 05 11.
Article em En | MEDLINE | ID: mdl-33976121
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / RNA de Transferência / Genoma Humano / Ilhas de CpG / Metilação de DNA Limite: Adolescent / Adult / Aged / Aged80 / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Envelhecimento / RNA de Transferência / Genoma Humano / Ilhas de CpG / Metilação de DNA Limite: Adolescent / Adult / Aged / Aged80 / Animals / Child / Child, preschool / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article