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Point-of-care haemoglobin testing in African hospitals: a neglected essential diagnostic test.
Uyoga, Sophie; George, Elizabeth C; Bates, Imelda; Olupot-Olupot, Peter; Chimalizeni, Yami; Molyneux, Elizabeth M; Maitland, Kathryn.
Afiliação
  • Uyoga S; Kenya Medical Research Institute (KEMRI), Wellcome Trust Research Programme, Kilifi, Kenya.
  • George EC; Medical Research Council Clinical Trials Unit (MRC CTU) at University College, London, UK.
  • Bates I; Liverpool School of Tropical Medicine, Liverpool UK, Liverpool, UK.
  • Olupot-Olupot P; Faculty of Health Sciences, Busitema University, Mbale Regional Referral Hospital, Mbale, Uganda.
  • Chimalizeni Y; College of Medicine, Malawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.
  • Molyneux EM; College of Medicine, Malawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.
  • Maitland K; Kenya Medical Research Institute (KEMRI), Wellcome Trust Research Programme, Kilifi, Kenya.
Br J Haematol ; 193(5): 894-901, 2021 06.
Article em En | MEDLINE | ID: mdl-33993492
ABSTRACT
Owing to the rapid turnaround time in the assessment of haemoglobin level by point-of-care tests (POC Hb), these have grown in popularity and scope in large parts of the world. However, whilst POC testing for malaria and HIV remains has been integrated into patient management in Africa, the use of POC haemoglobin testing remains neglected by health services. The main users of transfusions (paediatric, maternity and trauma services) present largely as emergencies. Ward-based POC Hb could result in more rapid and accurate diagnosis of anaemia, contributing to saving of lives and at the same time reduce unnecessary transfusions which deplete the limited supplies of donated blood in Africa. Severe anaemia requiring transfusion is a major cause of paediatric admission in Africa. At a dissemination meeting to discuss the results of a large phase III paediatric transfusion trial and steps to implementation of the findings participants strongly recommended that one of the most pressing actions required was to prioritise the use of POC haemoglobin testing. This would facilitate implementation of the new transfusion algorithm, developed at the meeting, which refines patient management including blood transfusions. We present the rationale for the strongly recommended prioritisation of POC Hb, using paediatric transfusion as an exemplar.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transfusão de Sangue / Algoritmos / Hemoglobinas / Testes Imediatos / Anemia Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male País como assunto: Africa Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Transfusão de Sangue / Algoritmos / Hemoglobinas / Testes Imediatos / Anemia Tipo de estudo: Clinical_trials / Diagnostic_studies Limite: Child / Child, preschool / Female / Humans / Infant / Male País como assunto: Africa Idioma: En Ano de publicação: 2021 Tipo de documento: Article